SISPROT is an integrated proteomics sample preparation technology based on a unique centrifugal pipette tip "Spintip", which can achieve all steps of one-stop proteomics sample preparation, starting from the original sample. It also includes protein sample pre-enrichment, reduction, alkylation, enzymatic hydrolysis and desalting, etc. The treated samples can be directly used for mass spectrometry detection. It has high sensitivity, high throughput and high stability, and is particularly suitable for low microgram or even nanogram protein samples.

Based on the exclusive patented SISPROT sample preparation technology, BayOmics has developed a series of distinctive proteomics application solutions: spatial visualization proteomics allows both immunofluorescence staining and high-depth mass spectrometry detection using the same tissue slice; cell type proteomics sorts different cell subpopulations, 1,000 cells per subpopulation, to performs mass spectrometry detection to explore cell interactions and signal transduction; functional proteomics on the other hand focuses more on drug targets, and detects the upstream and downstream of signal pathways through multiple proteomics and modification omics to discover important protein targets that actually perform different functions.

By deeply diving into the proteomic data of pancreatic cancer clinical samples, BayOmics has established a pancreatic cancer drug target database, which contains membrane proteins, tyrosine kinases and tyrosine phosphokinases of many key signal nodes, and provides authorization services for drug targets in the database for subsequent drug development. At present, BayOmics is further expanding the number of clinical patients in the pancreatic cancer database, and actively expanding to other cancers including nasopharyngeal carcinoma, esophageal cancer, liver cancer, gastric cancer, colorectal cancer, etc., to establish corresponding drug target databases.

Compared to the total number of identifications in the human proteome database: